|
KMID : 1031120150050010025
|
|
Journal of Epilepsy Research
2015 Volume.5 No. 1 p.25 ~ p.28
|
|
|
Mesial Temporal Lobe Epilepsy in Congenital Toxoplasmosis: A Case Report
|
|
Jeong Woo-Kyo
Joo Byung-Euk
Seo Ji-Hye
Mun Jun-Kyu
Kim Ju-Hyeon
Seo Dae-Won
|
|
|
Abstract
|
|
|
|
Toxoplasmosis is a rare disease caused by intracellular protozoan parasite, Toxoplasma gondii. Though most patients with toxoplasmosis are asymptomatic, congenital toxoplasmosis in the fetus can cause ocular involvement such as chorioretinitis and central nervous system disease including intracerebral calcification, nystagmus, hydrocephalus and microcephaly. Also, these brain lesions can cause seizure secondarily. Our patient was diagnosed with congenital toxoplasmosis, based on toxoplasma-specific serologic test with typical clinical symptoms, including chorioretinitis, nystagmus, hydrocephalus and cerebral palsy. Her brain imaging findings revealed not only the multifocal encephalomalacia, but also multifocal cerebral calcification including intracerebral calcification in left perihippocampal region. Her epileptogenic zone was defined as mesial temporal lobe including hippocampus on left side by seizure semiology, electroencephalogram and neuroimaging including single photon emission computed tomography and 18F-Fluorodeoxyglucose positron-emission tomography. Her seizures were refractory to multiple anti-epileptic drugs. We report a patient with congenital toxoplasmosis who showed intractable mesial temporal lobe epilepsy.
|
|
|
KEYWORD
|
|
|
Congenital toxoplasmosis, Temporal lobe epilepsy, Intracerebral calcification
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|